Figure 2. PPARγ Agonist Drugs.
TZDs like pioglitazone and rosiglitazone are potent PPARγ agonists (red), but other weaker or partial agonists share the TZD structure with different side chains (blue). There are additional structurally diverse non-TZD PPARγ agoinsts (green and purple), including dual agonists of PPARα and PPARγ (orange). See text for details.