. Author manuscript; available in PMC: 2015 Oct 14.

Published in final edited form as: Br J Nutr. 2014 Aug 27;112(7):1206–1213. doi: 10.1017/S0007114514001925

Table 2.

Hazard ratios (HR) for the association of plasma phospholipid α-linolenic acid with the risk of incident stroke and CHD among 2709 US adults (Hazard ratios and 95 % confidence intervals)

	Quintiles s									P for trend
	I	II		III		IV		V
	I	HR	95 % CI	HR	95 % CI	HR	95 % CI	HR	95 % CI
Total stroke
Person-years	6208		5792		6026		6132		6589
No. of cases	85		80		94		80		91
Age- and sex-adjusted	1·0 (ref.)	1·00	0·74, 1·36	1·11	0·83, 1·50	0·91	0·67, 1·24	0·98	0·73, 1·32	0·68
Additionally adjusted model^*	1·0 (ref.)	0·96	0·70, 1·31	1·10	0·81, 1·49	0·88	0·64, 1·20	0·97	0·71, 1·31	0·66
Ischaemic stroke
No. of cases	69		63		70		62		73
Age- and sex-adjusted	1·0 (ref.)	0·97	0·69, 1·37	1·03	0·74, 1·43	0·88	0·62, 1·24	0·97	0·70, 1·35	0·69
Additionally adjusted model^*	1·0 (ref.)	0·92	0·65, 1·30	1·01	0·72, 1·43	0·84	0·59, 1·20	0·97	0·69, 1·36	0·72
Haemorrhagic stroke
No. of cases	11		10		15		11		12
Age- and sex-adjusted	1·0 (ref.)	0·97	0·41, 2·28	1·38	0·63, 3·02	0·96	0·41, 2·22	0·99	0·44, 2·26	0·96
Additionally adjusted model^*	1·0 (ref.)	1·01	0·42, 2·43	1·45	0·65, 3·27	0·94	0·39, 2·26	0·95	0·40, 2·25	0·83
Total CHD
Person-years	6124		5756		5995		5928		6406
No. of cases	83		80		81		92		90
Age- and sex-adjusted	1·0 (ref.)	1·08	0·79, 1·47	1·09	0·80, 1·49	1·25	0·93, 1·68	1·14	0·85, 1·54	0·23
Additionally adjusted model^*	1·0 (ref.)	1·10	0·80, 1·50	1·10	0·80, 1·52	1·21	0·88, 1·64	1·22	0·90, 1·68	0·16

ref., Reference.

Additionally adjusted for race, enrolment site, education, smoking status, diabetes, BMI, waist circumference, physical activity, alcohol consumption and treated hypertension.