. Author manuscript; available in PMC: 2015 Oct 14.

Published in final edited form as: Br J Nutr. 2014 Aug 27;112(7):1206–1213. doi: 10.1017/S0007114514001925

Table 4.

Hazard ratios (HR) for the association of dietary α-linolenic acid with the risk of incident stroke and CHD among 2583 adults (Hazard ratios and 95 % confidence intervals)

	Quintiles									P for trend
	I	II		III		IV		V
	I	HR	95 % CI	HR	95 % CI	HR	95 % CI	HR	95 % CI
Total stroke
Person-years	4691		4785		4891		4997		5380
No. of cases	70		64		75		81		68
Age–sex- and energy-adjusted	1·0 (ref.)	0·86	0·61, 1·21	1·00	0·72, 1·39	1·05	0·76, 1·45	0·84	0·60, 1·17	0·69
Additionally adjusted model^*	1·0 (ref.)	0·89	0·64, 1·26	0·97	0·70, 1·35	1·09	0·78, 1·51	0·86	0·60, 1·21	0·80
Ischaemic stroke
No. of cases	59		52		54		67		46
Age–sex- and energy-adjusted	1·0 (ref.)	0·85	0·59, 1·23	0·85	0·59, 1·24	1·03	0·72, 1·47	0·67	0·45, 1·01	0·19
Additionally adjusted model^*	1·0 (ref.)	0·89	0·61, 1·30	0·84	0·58, 1·22	1·08	0·75, 1·54	0·70	0·47, 1·04	0·29
Haemorrhagic stroke
No. of cases	8		8		15		10		15
Age–sex- and energy-adjusted	1·0 (ref.)	1·26	0·44, 3·63	2·36	0·91, 6·08	1·57	0·57, 4·36	2·29	0·88, 5·99	0·09
Additionally adjusted model^*	1·0 (ref.)	1·19	0·41, 3·44	2·12	0·81, 5·54	1·52	0·54, 4·24	1·96	0·73, 5·27	0·16
Total CHD
Person-years	4631		4740		4815		4960		5321
No. of cases	77		71		67		92		71
Age–sex- and energy-adjusted	1·0 (ref.)	0·92	0·67, 1·27	0·87	0·63, 1·21	1·25	0·92, 1·70	0·92	0·66, 1·28	0·67
Additionally adjusted model^*	1·0 (ref.)	0·97	0·70, 1·34	0·88	0·63, 1·23	1·25	0·91, 1·70	0·93	0·67, 1·30	0·75

ref., Reference.

Additionally adjusted for race, enrolment site, education, smoking status, diabetes, BMI, alcohol consumption and treated hypertension.