Table 1. Patient Demographics and Tumor Characteristics.
| Total n=91* |
Non-Selective α Blockade n=71 |
Selective α Blockade n=16 |
p-value | |
|---|---|---|---|---|
|
| ||||
| Age | 52 (36-60) | 53 (36-61) | 47 (40-56) | 0.456 |
|
| ||||
| Gender | 0.580 | |||
| Male | 43 (47%) | 32 (45%) | 9 (56%) | |
| Female | 48 (53%) | 39 (55%) | 7 (44%) | |
|
| ||||
| BMI | 27.5 (25-30) | 27.5 (25-30) | 27.7 (23-29) | 0.809 |
|
| ||||
| ASA | 0.372 | |||
| 2 | 17 (19%) | 11 (16%) | 5 (31%) | |
| 3 | 65 (71%) | 52 (73%) | 10 (63%) | |
| 4 | 9 (10%) | 8 (11%) | 1 (6%) | |
|
| ||||
| Familial Syndrome | 1.00 | |||
| Yes | 22 (24%) | 17 (24%) | 4 (25%) | |
| No | 69 (76%) | 54 (76%) | 12 (75%) | |
|
| ||||
| Tumor Size (cm) | 4 (2.5-6.5) | 4.2 (3-6.5) | 3.8 (2.5-6.8) | 0.902 |
|
| ||||
| + Functional tumor | 1.000 | |||
| Yes | 82 (94%) | 65 (96%) | 16 (100%) | |
| No | 5 (6%) | 3 (4%) | 0 (0%) | |
|
| ||||
| **# Elevated Epinephrine | 0.539 | |||
| Yes | 60 (71%) | 47 (69%) | 13 (71%) | |
| No | 24 (29%) | 21 (31%) | 3 (19%) | |
|
| ||||
| **+ Elevated Norepinephrine | 1.000 | |||
| Yes | 75 (86%) | 60 (88%) | 15 (94%) | |
| No | 12 (14%) | 8 (12%) | 1 (6%) | |
|
| ||||
| Pre-blockade SBP | 137 (130-153) | 137 (130-150) | 161 (131-170) | 0.180 |
| Preoperative baseline SBP | 133 (120-143) | 135 (123-146) | 129 (120-140) | 0.829 |
|
| ||||
| Duration of alpha-blockade (days) | 34 (17-51) | 35 (19-52) | 38 (15-52) | 0.6966 |
Median values with interquartile range (IQR)
ASA, American Society of Anesthesiologists Physical Status Classification System; SBP, systolic blood pressure; BMI, body mass index;
*
, includes patients without blockade;
+
Four patients did not have catecholamine levels available;
#
Three additional patients were missing epinephrine levels but had norepinephrine levels available;
**
, Normalized: see text for details