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. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Cell Metab. 2014 Sep 25;20(4):593–602. doi: 10.1016/j.cmet.2014.08.012

Figure 2. Metabolic analyses in β-FoxO KO mice.

Figure 2

(A–B) Blood glucose and insulin levels in fasted, fed, and 4-hr-refed 12-week-old male mice (n=9 WT, 10 KO mice per genotype).

(C–E) Intraperitoneal glucose tolerance tests in male mice at different ages (n=12 WT, 8 KO mice per genotype at each age).

(F) Quantification of areas under the curve for the experiments shown in c-e.

(G–I) Hyperglycemic clamps in 24-week-old male mice, showing glucose infusion rates

(G), plasma insulin levels (I) and quantification of areas under the curve for the experiments shown in h and i (n=4 mice per genotype). All data are presented as means ± SEM. *p<0.05, **p<0.01, ***p<0.001 by two-way ANOVA.