Table 4.

Raw (unstandardized) regression coefficients (b) and standard error (SE) summarizing associations between overall variability in BP^* (SD) and cognitive functioning measures, stratified by hypertension status^†

Cognitive outcome	Predictor	Hypertension, controlled,† n=289 (29.7%)			Hypertension, uncontrolled,† n=195 (20.1%)
		b	SE	P	b	SE	P
Global Composite	Variability SBP	−.010	.014	.490	−.040	.017	.021
	Variability DBP	−.021	.024	.386	−.073	.023	.002
Visual Spatial Memory and Organization	Variability SBP	−.014	.015	.354	−.029	.018	.097
	Variability DBP	−.028	.026	.277	−.085	.023	<.001
Similarities	Variability SBP	−.001	.016	.932	−.045	.019	.020
	Variability DBP	.033	.027	.226	−.072	.026	.005
Mini-Mental State Examination	Variability SBP	−.006	.014	.696	−.070	.022	.002
	Variability DBP	.002	.024	.935	−.058	.030	.057

DBP indicates diastolic blood pressure; SBP, systolic blood pressure.

Presented data are for the extended model; regression coefficients were adjusted for age, education, gender, ethnicity, diabetes, pulse pressure, BMI, total cholesterol, smoking (Y/N), alcohol (Y/N).

^*Overall variability calculated as the SD of all 15 individual BP measures.

^†Hypertension defined as BP ≥140/90 mmHg or being treated with anti-hypertensive medication; controlled defined as BP <140/90 mmHg while on medication; uncontrolled defined as BP ≥140/90 mmHg while on medication.