Table III.
Predictors of interest in cffDNA screening for trisomy (N=3164)
| Demographic or experiential variable | Odds ratio | Wald χ2 statistic | p-value* |
|---|---|---|---|
| Gender | N.S. | ||
| Age | N.S. | ||
| Ethnicity | |||
| Hispanic or Latino | N.S. | ||
| Race | |||
| American Indian or Alaska Native | N.S. | ||
| Asian | N.S. | ||
| Black or African-American | N.S. | ||
| Native Hawaiian or Pacific Islander | N.S. | ||
| White | N.S. | ||
| Educational attainment | 1.171 | 20.476 | <0.001† |
| Household income | 1.271 | 46.866 | <0.001 |
| Health insurance status | 1.594 | 12.816 | <0.001† |
| Religion | |||
| Catholic | N.S. | ||
| Evangelical Protestant | N.S. | ||
| Other Protestant | N.S. | ||
| Mormon | N.S. | ||
| Jewish | 2.020 | 8.689 | 0.003† |
| Buddhist | N.S. | ||
| Muslim | N.S. | ||
| Unaffiliated | N.S. | ||
| Religiosity | 0.886 | 6.192 | 0.013† |
| Experience as a parent | N.S. | ||
| Experience with physical disability | N.S. | ||
| Experience with mental illness or disability | N.S. | ||
| Experience with doctor-ordered genetic test | 1.499 | 6.671 | 0.010† |
| Experience with purchased genetic test | 1.591 | 6.231 | 0.013† |
| Consideration of pregnancy termination | 1.619 | 24.908 | <0.001 |
*
N.S.=not significant. All p-values are reported using logistic regressional analysis adjusting for whether respondents were queried regarding trisomy 13 and 18 or trisomy 21.
†
This predictive variable does not remain significant in a multivariate logistic regression of all individually significant predictors of interest.