Table 3. Mean baseline values and the mean absolute changes in anthropometry and blood pressure in the treatment and placebo group.

		Mean Change from Baseline (95% CI)			P value*
	Baseline	▵ 2 months	▵ 4 months	▵ 6 months	Time	Treatment	Interaction
Weight, kg
Treatment (n = 35)	85.7 (18.2)	−0.05 (−0.56, 0.46)	−0.03 (−0.75, 0.69)	−0.02 (−0.79, 0.75)	0.13 (0.41)	0.68 (0.35)	0.05 (0.29)
Placebo (n = 45)	87.9 (21.2)	0.69 (0.31, 1.07)	0.54 (−0.06,1.14)	0.49 (−0.27, 1.25)
WC, cm
Treatment (n = 35)	103.0 (11.5)	0.56 (−0.29, 1.42)	0.30 (−0.51, 1.11)	−0.85 (−1.78, 0.07)	0.66 (<0.01)	0.28 (0.06)	0.69 (0.95)
Placebo (n = 45)	108.4 (15.3)†	0.84 (−0.01, 1.69)	0.22 (−0.48, 0.93)	−0.59 (−1.60, 0.42)
SBP, mmHg
Treatment (n = 35)	120.8 (14.0)	−0.11 (−4.90, 4.68)	0.91 (−3.73, 5.56)	2.44 (−0.95, 5.83)	0.06 (0.99)	0.38 (0.11)	0.68 (0.39)
Placebo (n = 45)	126.8 (12.1)†	−0.49 (−4.16, 3.19)	−1.20 (−5.10, 2.69)	−2.18 (−6.16, 1.80)
DBP, mmHg
Treatment (n = 35)	73.1 (10.0)	−0.11 (−4.15, 3.92)	−0.66 (−5.65, 4.32)	−0.20 (−3.71, 3.30)	0.38 (0.54)	0.24 (0.23)	0.31 (0.30)
Placebo (n = 45)	76.8 (8.9)†	2.24 (−0.67, 5.15)	−1.36 (−3.93, 1.22)	−1.56 (−4.33, 1.22)

Baseline data are presented as mean (SD).

*A multivariate 2-factor repeated-measures regression analysis was used to assess time effects and time by treatment effect interactions on all outcome variables after adjustment for the variables that were different between treatment groups at baseline. Numbers in brackets represent unadjusted P values.

^† P<0.1 for the difference between groups at baseline (unpaired t test or Wilcoxon, as appropriate).

DBP, diastolic blood pressure; SBP, systolic blood pressure; WC, waist circumference.