Table 3.

 Vaccination strategies modelled with base case vaccination parameters in re-assessment of cost effectiveness of vaccination (Bexsero) against meningococcal disease

Routine strategy	Months of protection* after priming (booster) dose	One-off catch up	Months of protection after catch up
Routine infant
2, 3, 4, and 12 months	18 (36)	—	—
2, 3, 4, and 12 months†	18 (36)	—	—
2, 4, and 12 months	18 (36)	—	—
2, 3, 4, and 12 months	18 (36)	1-4 years‡	60
Routine adolescent
13 years‡	120	—	—
13 years	120	14-17 years‡	120
Routine infant and adolescent
2, 3, 4, and 12 months; 13 years	18 (36); 120	—	—
2, 4, and 12 months; 13 years	18 (36); 120	—	—
Switching strategy§	See above for individual strategies

*Waning protection from vaccination implemented as rate equal to 1/months protection.

†Additional component: remove costs of infant meningococcal group C conjugate vaccine

‡Vaccination in adolescents and catch-up cohorts modelled as two dose schedule, two months apart.

§Switching strategy consisted of vaccination at 2, 3, 4, and 12 months and 13 years, switching after 10 years to 2, 4, and 12 months and 13 years.