Table 3. Associations between Immunological and Microbiological Findings.
| Bacterial Species | Immunological Finding | Association | p | Interpretation |
| P. gingivalis (n = 3) | SI IL-1β E.coli LPS | positive | 0.019 | 1 |
| SI IL-8 E.coli LPS | positive | 0.029 | 1 | |
| SI IL-8 P.g. LPS | positive | 0.015 | 1 | |
| CD4/CD8 ratio | negative | 0.023 | 1 | |
| IFN-γ producing T-helper cells | positive | 0.023 | 1 | |
| IFN-γ/IL-4 ratio | positive | 0.015 | 1 | |
| F. nucleatum (n = 20) | B-cells | negative | 0.030 | 2 |
| naïve and transitional B-cells | negative | 0.050 | 2 | |
| switched memory B-cells | positive | 0.014 | 2 | |
| memory B-cells | positive | 0.018 | 2 | |
| A. prevotii (n = 4) | SI IL-1β E.coli LPS | negative | 0.007 | 3 |
| A. meyeri (n = 12) | B-cells | negative | 0.049 | 4 |
| P. disiens (n = 2) | SI IL-1β P.g. LPS | positive | 0.029 | 5 |
| IFN-γ/IL-4 ratio | positive | 0.029 | 5 | |
| C. rectus (n = 2) | SI IL-1β E.coli LPS | negative | 0.038 | 3 |
| IFN-γ producing T-helper cells | negative | 0.019 | 3 | |
| E. limosum (n = 2) | naïve and transitional B-cells | positive | 0.013 | 2 |
| B-cells | positive | 0.013 | 2 | |
| Finegoldia magna (n = 2) | B-cells | positive | 0.013 | 6 |
| IFN-γ/IL-4 ratio | negative | 0.019 | 6 | |
| SI IL-8 E.coli LPS | negative | 0.038 | 6 | |
| IL-4 producing T-helper cells | positive | 0.038 | 6 | |
| P. oralis (n = 14) | switched memory B-cells | negative | 0.035 | 2 |
| IFN-γ/IL-4 ratio | negative | 0.035 | 2 | |
| P. buccalis (n = 2) | CD4/CD8 ratio | positive | 0.003 |
n: positive identifications from the 46 microbiologically characterized individuals; SI: stimulation index;
1
activation of Th1-response;
2
activation of B-cell-maturation;
3
negative regulation of innate immunity;
4
no B-cell stimulation;
5
positive regulation of innate immunity;
6
activation of humoral immunity (Th2).