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. 2014 Sep 13;30(Suppl 1):440–444. doi: 10.1007/s12288-014-0458-1

Table 3.

Summary of outcome in reported pregnancies with anti Cw

Reference No of cases Clinical outcome
Lawler and Loghem [3] 1 HDN
Anderson et al. [4] 9 pregnancies in a anti Cw positive woman First child normal, Cw positive
Second and third child (twins) had jaundice, Cw positive, required transfusion
Fourth child normal, Cw negative
Next four pregnancy miscarriage
Fifth child had jaundice, Cw positive, no transfusion required
Hughes et al. [5] NM Severe HDF, treated with phototherapy and exchange transfusion
Bowman et al. [6] 14 pregnancies with acquired anti Cw (In 1 in 1,100 women treated during 36 years) Three babies who were Cw negative- normal
11 babies were Cw positive- DAT+had HDN
(Five no treatment required, two required phototherapy and four required exchange transfusion)
Reiner et al. [7] 1 Required phototherapy and exchange transfusion
Kollamparambil et al. [8] NM Severe HDF, fetus had hydrops.
Byers et al. [9] 1 Severe fetal anemia requiring intrauterine transfusion
May-Wewers et al. [10] 1 Severe neonatal anemia
Chu et al. [11] NM History of previous IUD and bad obstetrics history. Presenting pregnancy had HDN and neonate required exchange transfusion
Malik [12] 1 (Primi) Normal baby
1 (4th gravida) Normal baby
1 (Primi) NM

DAT direct ant globulin test, NM not mentioned, IUD intra uterine transfusion, HDF hemolytic disease of fetus, HDN hemolytic disease of newborn