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. 2014 Oct 9;9(10):e109043. doi: 10.1371/journal.pone.0109043

Table 2. Occurrence of stapes-facial canal connectivity in adult Pou3f4 and Efnb2 single and compound mutant mice.

Genotype n a Soft Tissue Bridge Bone Bridge Total Affected
Pou3f4 Cre/Y; Efnb2 +/+ 40 18 (.45) 13 (.33) 31 (.78)
Pou3f4 Cre/Y; Efnb2 +/flox 38 9 (.24) 13 (.34) 22 (.57)
Pou3f4 Cre/Y; Efnb2 null/+ 32 10 (.31) 8 (.25) 18 (.56)
Pou3f4 Cre/Y; Efnb2 null/flox 39 1** (.03) 23* (.59) 24 (.62)
Pou3f4 +/Y; Efnb2 null/+ 30 0 0 0
Pou3f4 +/Y; Efnb2 +/+ 62 0 0 0
a

sample size refers to the number of ears analyzed.

* 0.02<P<0.05;

** p<0.0001; all pairwise Fisher's exact tests were performed relative to the Pou3f4 Cre/Y; Efnb2 +/+ genotype. Statistical significance set at P<0.05.