Table 2. Occurrence of stapes-facial canal connectivity in adult Pou3f4 and Efnb2 single and compound mutant mice.
Genotype | n a | Soft Tissue Bridge | Bone Bridge | Total Affected |
Pou3f4 Cre/Y; Efnb2 +/+ | 40 | 18 (.45) | 13 (.33) | 31 (.78) |
Pou3f4 Cre/Y; Efnb2 +/flox | 38 | 9 (.24) | 13 (.34) | 22 (.57) |
Pou3f4 Cre/Y; Efnb2 null/+ | 32 | 10 (.31) | 8 (.25) | 18 (.56) |
Pou3f4 Cre/Y; Efnb2 null/flox | 39 | 1** (.03) | 23* (.59) | 24 (.62) |
Pou3f4 +/Y; Efnb2 null/+ | 30 | 0 | 0 | 0 |
Pou3f4 +/Y; Efnb2 +/+ | 62 | 0 | 0 | 0 |
sample size refers to the number of ears analyzed.
* 0.02<P<0.05;
** p<0.0001; all pairwise Fisher's exact tests were performed relative to the Pou3f4 Cre/Y; Efnb2 +/+ genotype. Statistical significance set at P<0.05.