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. 2014 Oct 9;9(10):e109527. doi: 10.1371/journal.pone.0109527

Figure 5. Triheptanoin diet improves insulin sensitivity in Mecp2 KO mice.

Figure 5

(A–C): Blood glucose levels after intraperitoneal insulin injection (1 unit/kg) at 4 weeks (A), 6 weeks (B), and 8 weeks of age (C) in chow-fed WT or Mecp2 KO mice (WT vs. KO *p<0.05, **p<0.01, ***p<0.001; two-way ANOVA with Bonferroni post hoc test; 4 wk CHOW WT n = 6, 4 wk CHOW KO n = 8. (D, E): Blood glucose levels after intraperitoneal insulin injection (1 unit/kg) at 6 weeks (D) and 8 weeks (E) of age after two (D) or four (E) weeks of SBO or triheptanoin diet in WT or Mecp2 KO mice (SBO-KO vs. other groups *p<0.05, **p<0.01, ***p<0.001; two-way ANOVA with Bonferroni post hoc test; n = 4 per group). All graphs represent mean±s.e.m.