Table 2.
Respondents’ support of clinical trial data sharing, stratified by trialist and trial characteristics
| ‘The clinical research community should promote and facilitate clinical trial data sharing’ | ||||
|---|---|---|---|---|
| Respondents | Agree (%) | Disagree (%) | Pvalue | |
| Overall | 317 | 278 (88) | 39 (12) | |
| Trialist academic productivity (number of research articles published in past three years) | 0.22 | |||
| 1 to 10 articles | 71 | 66 (93) | 5 (7) | |
| 11 to 25 articles | 117 | 103 (88) | 14 (12) | |
| >25 articles | 129 | 109 (85) | 20 (16) | |
| Trialist geographic location | 0.17* | |||
| United States or Canada | 167 | 141 (84) | 26 (16) | |
| Western Europe | 113 | 104 (92) | 9 (8) | |
| Other | 37 | 33 (89) | 4 (11) | |
| Trial funding source | 0.07* | |||
| Government | 120 | 108 (90) | 12 (10) | |
| Industry or mixed funding | 152 | 127 (84) | 25 (16) | |
| Other | 45 | 43 (96) | 2 (4) | |
| Trial size | 0.71 | |||
| ≤239 subjects | 80 | 69 (86) | 11 (14) | |
| 240 to 2,016 subjects | 158 | 141 (89) | 17 (11) | |
| ≥2,017 subjects | 79 | 68 (86) | 11 (14) | |
| Journal in which the trial was published | 0.01* | |||
| NEJM | 113 | 92 (81) | 21 (19) | |
| Lancet | 70 | 61 (87) | 9 (13) | |
| JAMA | 43 | 36 (84) | 7 (16) | |
| Annals of Internal Medicine | 24 | 23 (96) | 1 (4) | |
| The BMJ | 53 | 52 (98) | 1 (2) | |
| PLoS Medicine | 14 | 14 (100) | 0 (0) | |
*Fisher exact test. JAMA, Journal of the American Medical Association; NEJM, New England Journal of Medicine.