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. 2014 Sep 26;15(1):815. doi: 10.1186/1471-2164-15-815

Table 3.

Comparison of differentially expressed genes between imipenem-selected mutants (this study) and biofilm-associated ATCC 17978 cells as decribed by Rumbo-Feal et al. (12)

Locus tag Log2 (fold change) in IPM-2 m Log2 (fold change) in IPM-8 m Log2 (fold change) biofim vs.expotenetial phase cells a Protein Name
Inverse expressed between imipenem-resistant mutants and biofilm-associated cells
NameA1S_0087 -3.76 -4.52 1.36 Short-chain dehydrogenase/reductase SDR
A1S_0109 -3.62 -6.03 5.91 Homoserine lactone synthase
A1S_0112 -1.86 -4.76 6.23 Acyl-CoA synthetase/AMP-acid ligases II
A1S_0115 -2.47 -5.27 7.24 Amino acid adenylation
A1S_0116 -2.97 -6.01 5.81 RND superfamily transporter
A1S_0117 -1.38 -2.92 4.58 Hypothetical protein A1S_0117
A1S_0118 -2.01 -4.06 3.21 Hypothetical protein A1S_0118
A1S_2214 -2.40 -3.86 7.49 CsuD
A1S_2215 -3.14 -4.57 7.65 CsuC
A1S_2218 -3.89 -5.88 7.36 CsuA/B
Overexpressed both in imipenem-resistant mutants and biofilm-associated cells
A1S_0538 4.48 0.39 2.72 RND efflux transporter
A1S_2534 3.34 2.02 4.40 Sulfate transport protein
A1S_0032 7.09 0.49 5.01 Putative signal peptide
A1S_2889 6.72 1.25 5.54 Putative signal peptide
HHS Vulnerability Disclosure