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. 2014 Oct 9;10(10):e1004423. doi: 10.1371/journal.ppat.1004423

Figure 7. The differential translation of EBNA1 mRNAs impacts on the activation and functional programming of antigen-specific T cells.

Figure 7

Female C57BL/6 mice were immunized intramuscularly with Ad-E1-GArN-GFP or Ad-E1-GArM-GFP virus (A–B). Mice were sacrificed on day 7 post-infection and spleen cells harvested to evaluate the activation and functions of antigen-specific CD8+ T cells. (A) Expression of T cell activation markers CD44, CD62L and CD69. (B) Expression of IFN-γ, TNF-α and translocation of CD107α by Ag-specific CD8+ OT-1 cells. Mean ± SD shown (n = 5).