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DNA methylation in Neurospora. The current model for DNA methylation in Neurospora suggests a multistep process that starts with DIM-5 recruitment and H3K9 methylation mediated by the DCDC complex. Once the H3K9me3 is established, HP1 in association with DIM-2 and binds to H3K9me3 via its chromodomain, and then, DIM-2 catalyzes 5mC.
