Table 2. CSF and plasma Aβ42 levels in patients with severe TBI acutely after injury and in controls. Data are given as median (interquartile range).
N | CSF Aβ42 (pg/mL) | N | Plasma Aβ42 (pg/mL) | ||
---|---|---|---|---|---|
TBI | Admission | 12 | 105.9 (46.02–216.2)† | 12 | 17.02 (14.75–28.59)† |
Diffuse Injury (Admission) | 6 | 105.9 (52.45–227.6) | 6 | 19.65 (14.91–32.90) | |
Focal Mass Lesion (Admission) | 6 | 118.7(16.59–239.3) | 6 | 16.61 (13.21–27.35) | |
Survivors (Admission) | 6 | 161.1 (65.67–286.9)° | 6 | 16.29 (14.13–18.88)° | |
Non-Survivors (Admission) | 6 | 46.02 (11.55–172.4)‡ | 6 | 27.97 (13.66–32.90)‡ | |
Controls | 15 | 537.6 (350.8–710.0) | 20 | 7.289 (6.126–8.668) |
†p < .0001 (p values of the Mann-Whitney test for differences between the groups [TBI versus Controls]).
°p < .05, or ‡ p < .0001 (p values of the post-hoc test for differences between Survivors and Non-survivors versus Controls).