Table 2.
Associations of age at menarche, menstrual characteristics, and adult onset asthma
| Adult onset asthma | Unadjusted | Adjusted* | ||
|---|---|---|---|---|
| Characteristics | Yes (N=261) |
No (N=3200) |
RR 95% (CI) | RR 95% (CI) |
| Early Menarche* | ||||
| No | 206 (78.93) | 2749 (85.91) | Referent | Referent |
| Yes | 55 (21.07) | 451 (14.09) | 1.56 (1.17,2.07) | 1.59 (1.19,2.13) |
| P- value | 0.002 | 0.002 | ||
| Regular Menses | ||||
| Yes | 219 (85.88) | 2732 (85.38) | Referent | Referent |
| No | 36 (14.12) | 468 (14.63) | 0.96 (0.68,1.35) | 0.95 (0.67,1.34) |
| P- value | 0.825 | 0.774 | ||
| Menstrual Cycle Length (days) | ||||
| <24 | 10 (3.83) | 156 (4.88) | 0.79 (0.43,1.46) | 0.81 (0.44,1.51) |
| 25 – 30 | 193 (73.95) | 2341 (73.16) | Referent | Referent |
| 31 – 35 | 34 (13.03) | 445 (13.91) | 0.93 (0.65,1.32) | 0.88 (0.61,1.27) |
| ≥36 | 24 (9.20) | 258 (8.06) | 1.11 (0.74,1.67) | 1.08 (0.71,1.63) |
| Trend P- value | 0.238 | |||
*
Adjusted for age, race/ethnicity, BMI at age 18 years, educational status, smoking, physical activity between ages 13 – 17 years, parity, history of diabetes and history of hypertension