Table 1.
Succinated proteins in HLRCC cancers and derived cell lines.
| Uniprot ID | Protein Symbol | Protein Name | Succination Site | Source |
|---|---|---|---|---|
| P53396 | ACLY | ATP-citrate synthase | C20 | T, N |
| Q09666 | AHNAK | Neuroblast differentiation-associated protein AHNAK | C1833 | T, N |
| P15121 | AKR1B1 | Aldose reductase | C299 | T |
| P54886-1 | ALDH18A1 | Isoform Long of Delta-1-pyrroline-5-carboxylate synthase | C612 | T, U, N |
| Q5TYW2 | ANKRD20A1 | Ankyrin repeat domain-containing protein 20A1 | C789 | N |
| P04083 | ANXA1 | Annexin A1 | C324 | T, U |
| P16615-1 | ATP2A2 | Isoform 1 of Sarcoplasmicendoplasmic reticulum calcium ATPase 2 | C997 | N |
| Q86VP6-1 | CAND1 | Isoform 1 of Cullin-associated NEDD8-dissociated protein 1 | C942 | U |
| P20810-2 | CAST | Isoform 2 of Calpastatin | C408, C413 | N |
| P23528 | CFL1 | Cofilin-1 | C139 | T, U |
| Q9NX63 | CHCHD3 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial | C112 | T |
| Q8N5K1 | CISD2 | CDGSH iron-sulfur domain-containing protein 2 | C92 | T |
| Q00610-1 | CLTC | Isoform 1 of Clathrin heavy chain 1 | C870 | U, N |
| P55060-1 | CSE1L | Isoform 1 of Exportin-2 | C272 | U, N |
| Q6NSH3 | CT45A5 | Cancertestis antigen family 45 member A5 | C22 | U |
| Q9UBR2 | CTSZ | Cathepsin Z | C92 | U |
| Q9H773 | DCTPP1 | dCTP pyrophosphatase 1 | C162 | T |
| P17844 | DDX5 | Probable ATP-dependent RNA helicase DDX5 | C200 | U |
| P33316-2 | DUT | Isoform 2 of Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | C3 | N |
| P07814 | EPRS | Bifunctional aminoacyl-tRNA synthetase | C105 | T, U |
| O95571 | ETHE1 | Protein ETHE1, mitochondrial | C170 | T, U, N |
| P21333-2 | FLNA | Isoform 2 of Filamin-A | C717, C2543 | T, U, N |
| O75369-1 | FLNB | Isoform 1 of Filamin-B | C2501 | N |
| Q9HA64 | FN3KRP | Ketosamine-3-kinase | C24 | T |
| P02794 | FTH1 | Ferritin heavy chain | C91 | T |
| P04406 | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | C152 | T, U, N |
| P07203 | GPX1 | Glutathione peroxidase 1 | C202 | T |
| P53701 | HCCS | Cytochrome c-type heme lyase | C39 | U, N |
| P00492 | HPRT1 | Hypoxanthine-guanine phosphoribosyltransferase | C106 | T |
| Q14197 | ICT1 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | C82 | N |
| Q9NWZ3 | IRAK4 | Isoform 1 of Interleukin-1 receptor-associated kinase 4 | C13 | U, N |
| O14880 | MGST3 | Microsomal glutathione S-transferase 3 | C150, C151 | T, N |
| P46013-1 | MKI67 | Isoform Long of Antigen KI-67 | C1285 | U |
| P35579-1 | MYH9 | Isoform 1 of Myosin-9 | C988 | T, U, N |
| Q9NX24 | NHP2 | HACA ribonucleoprotein complex subunit 2 | C18 | T |
| P53384-1 | NUBP1 | Isoform 1 of Cytosolic Fe-S cluster assembly factor NUBP1 | C22, C25 | T |
| Q9H6K4-1 | OPA3 | Isoform 1 of Optic atrophy 3 protein | C164 | N |
| Q99497 | PARK7 | Protein DJ-1 | C106 | T, N |
| Q9Y570-1 | PPME1 | Isoform 1 of Protein phosphatase methylesterase 1 | C381 | N |
| Q06830 | PRDX1 | Peroxiredoxin-1 | C173 | T |
| P30048 | PRDX3 | Thioredoxin-dependent peroxide reductase, mitochondrial | C108 | T |
| P30041 | PRDX6 | Peroxiredoxin-6 | C91 | T, U, N |
| Q15185 | PTGES3 | Prostaglandin E synthase 3 | C58 | T, U, N |
| P49023-2 | PXN | Isoform Alpha of Paxillin | C535, C538 | U |
| P63000-1 | RAC1 | Isoform A of Ras-related C3 botulinum toxin substrate 1 | C178 | T |
| P54727 | RAD23B | UV excision repair protein RAD23 homolog B | C390 | U |
| P50914 | RPL14 | Ribosomal protein L14 variant | C42 | T |
| P05386 | RPLP1 | 60S acidic ribosomal protein P1 | C61 | T |
| P31947-1 | SFN | Isoform 1 of 14-3-3 protein sigma | C38 | T, U, N |
| Q15005 | SPCS2 | Signal peptidase complex subunit 2 | C17, C26 | T, U, N |
| P42224-1 | STAT1 | Isoform Alpha of Signal transducer and activator of transcription 1-alphabeta | C492 | N |
| Q00059 | TFAM | Transcription factor A, mitochondrial | C246 | T, N |
| Q12931 | TRAP1 | Heat shock protein 75 kDa, mitochondrial | C573 | N |
| Q9H4B7 | TUBB1 | Tubulin beta-1 chain | C12 | T, U, N |
| P10599 | TXN | Thioredoxin | C73 | T |
| P09936 | UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | C90 (T), C152 (T, U) | T, U |
| P45880-2 | VDAC2 | Isoform 2 of Voltage-dependent anion-selective channel protein 2 | C76 | T, U, N |
| Q9Y277-1 | VDAC3 | Isoform 1 of Voltage-dependent anion-selective channel protein 3 | C65 | T, U, N |
| P08670 | VIM | Vimentin | C328 | T |
| P54577 | YARS | Tyrosyl-tRNA synthetase, cytoplasmic | C424 | U |