Table 4.

Multivariable analysis for role of adherence in relapse risk in African-American, Asian-American, and non-Hispanic white children with ALL

Variables	HR (95% CI)	P*
NCI criteria for disease risk
Standard-risk disease	1.0	—
High-risk disease	1.2 (0.5-3.2)	.7
6MP dose intensity
Per unit increase in dose intensity	0.99 (0.97-1.01)	.3
Blast chromosomal abnormalities
Normal/ none	1.0	—
Favorable	0.3 (0.08-1.2)	.1
Unfavorable	2.1 (0.4-10.1)	.4
Adherence to oral 6MP
≥90%	1.0	—
<90%	3.9 (1.3-11.3)	.01

Analysis was adjusted for time from initiation of maintenance to study entry, and race.

^*— indicates not applicable.