Fig. 2.

Fate of 44 patients with macroprolactinomas according to early response. (A) Overall progress of patients according to categorization by early response. (B) Prolactin (PRL) levels of the patients in group 2. Black line indicates patients who eventually achieved normalization of prolactin level (NP; delayed response subgroup); gray line, patients who did not achieve NP (sustained resistance subgroup). TVR, tumor volume reduction. ^aP<0.05 between the subgroups, the P value was calculated with the Mann-Whitney U test.