Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 15;9(16):1493–1497. doi: 10.4103/1673-5374.139470

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Upper extremity motor score (UEMS): Phase I/IIa Cethrin trial data vs. historical results.

(A) Change in UEMS over time. The average change in UEMS from baseline is displayed at 0, 0.5, 6, 12, 26, and 52 week intervals after initial examination for cethrin-treated cervical subjects in the three highest dose groups (phase I/IIa trial: 3, 6, and 9 mg doses, n = 9), and at 0, 4, 8, 16, 26, and 52 week intervals for historical cervical subjects in the Sygen database (n = 187, C_5–7). (B) Change in UEMS at 1 year after SCI. The average change in UEMS from baseline to 1 year post-injury is displayed for cethrin-treated cervical subjects (phase I/IIa trial: n = 16 for all doses [0.3, 1, 3, 6, 9 mg], n = 9 for 3 highest doses 3, 6, 9 mg]) and comparative historical cervical populations analyzed in the literature (Sygen database [n = 187, C_5–7], Model systems [n = 315]). Missing data points for dropouts were calculated using the method of Last Observation Carried Forward. Error bars represent standard error.