Table 1.
Abbreviated Gene Ontology table showing annotations of selected experimentally characterized gene products associated with advanced biofuel production.
| Gene product | Ontology* | GO term | Evidence† | Taxon | Reference |
| Butanol biosynthetic process | |||||
| GO:0071271 | |||||
| Thl | F | GO:0003985: acetyl-CoA acetyltransferase activity | IDA | 1488 | PMID:16347774 |
| Hbd | F | GO:0008691: 3-hydroxybutyryl-CoA dehydrogenase activity | IDA | 1520 | PMID:1444364 |
| Crt | F | GO:0003859: 3-hydroxybutyryl-CoA dehydratase activity | IDA | 1488 | PMID:16346566 |
| Bcd | F | GO:0004085: butyryl-CoA dehydrogenase | IDA | 1488 | PMID:8655474 |
| BYDH | F | GO:0004029: aldehyde dehydrogenase (NAD) activity | IDA | 1488 | PMID:8300540 |
| BDH | F | GO:0004022: alcohol dehydrogenase activity | IDA | 272562 | PMID:11790753 |
| Isobutanol biosynthetic process | |||||
| GO:1901961 | |||||
| Bat1 | F | GO:0004084: branched-chain aminotransferase activity | IDA | 4932 | PMID:8798704 |
| Bat1 | C | GO:0005739: mitochondrion | IDA | 4932 | PMID:8798704 |
| Bat2 | F | GO:0004084: branched-chain aminotransferase | IDA | 4932 | PMID:8798704 |
| Bat2 | C | GO:0005829: cytosol | IDA | 4932 | PMID:8798704 |
| PDC | F | GO:0004737: pyruvate decarboxylase | IMP | 4932 | PMID:9546164 |
| ADH2 | F | GO:0004022: alcohol dehydrogenase activity | IMP | 4932 | PMID:3546317 |
| Isopropanol biosynthetic process | |||||
| GO:1902639 | |||||
| THL | F | GO:0003985: acetyl-CoA acetyltransferase activity | IDA | 1488 | PMID:16347774 |
| CTF | F | GO:0008410: CoA-transferase activity | IDA | 1488 | PMID:2719476 |
| ADC | F | GO:0047602: Acetoacetate decarboxylase activity | IDA | 272562 | PMID:2268159 |
| SADH | F | GO:0004022: alcohol dehydrogenase activity | IDA | 1520 | PMID:8349550 |
| Tolerance | |||||
| ARI1 | P | GO:1990370: process resulting in tolerance to aldehyde | |||
| Spo0A | P | GO:1990336: process resulting in tolerance to butanol | IDA | 1488 | PMID:15028679 |
| Cfa | P | GO:1990336: process resulting in tolerance response to butanol | IDA | 1350 | PMID:24014527 |
| Cfa | P | GO:1990337: process resulting in tolerance to isobutanol | IDA | 1350 | PMID:24014527 |
| Sll0690 | P | GO:1990336: process resulting in tolerance to butanol | IMP | 1148 | PMID:23883549 |
| Slr0947 | P | GO:1990336: process resulting in tolerance to butanol | IMP | 1148 | PMID:23883549 |
| slr1295 | P | GO:1990336: process resulting in tolerance to butanol | IMP | 1148 | PMID:23883549 |
*Molecular function (F), biological process (P), cellular component (C).
†Inferred from direct assay (IDA), inferred from mutant phenotype (IMP).