Table 5.
Category-Free Net Reclassification Improvement Over the Baseline Cardiovascular Risk Factors Model
| Model | Overall NRI
|
Event NRI, % | Nonevent NRI, % | |
|---|---|---|---|---|
| NRI, % | P Value | |||
| All-cause mortality | ||||
| BRF* | ref | ref | ref | ref |
| BRF + distance score | 44.4 | <0.001 | 9.3 | 35.1 |
| BRF + stair-climbing score | 47.5 | <0.001 | 33.7 | 13.7 |
| BRF + speed score | 32.2 | <0.001 | 19.8 | 12.4 |
| BRF + all 3 scores | 48.4 | <0.001 | 24.4 | 24.0 |
| Cardiovascular mortality | ||||
| BRF | ref | ref | ref | ref |
| BRF + distance score | 60.3 | <0.001 | 23.4 | 36.9 |
| BRF + stair-climbing score | 84.0 | <0.001 | 61.7 | 22.3 |
| BRF + speed score | 51.5 | 0.001 | 27.7 | 23.9 |
| BRF + all 3 scores | 77.4 | <0.001 | 48.9 | 28.5 |
BRF indicates baseline risk factors; NRI, net reclassification improvement; and ref, reference.
Age, sex, race, smoking history, body mass index, systolic blood pressure, use of lipid-lowering medication, use of antihypertensive medication, diabetes mellitus status, total cholesterol, high-density lipoprotein-cholesterol, and ankle-brachial index.