Table 2.
Task-induced effective connectivity
| Control |
PD-OFF |
PD-ON |
||||
|---|---|---|---|---|---|---|
| Connection | Frequency (peak activation) | P-value (FWE-corr.) | Frequency (peak activation) | P-value (FWE-corr.) | Frequency (peak activation) | P-value (FWE-corr.) |
| lPM → M1 | γ-γ (35–36 Hz) | 0.003 | γ-γ (39–35 Hz) | 0.01 | γ-γ (32–32 Hz) | 0.021 |
| lPM → SMA | γ-γ (35–33 Hz) | 0.018 | – | – | γ-γ (35–31 Hz) | <0.001 |
| β-β (17–18 Hz) | 0.024 | |||||
| M1 → lPM | – | – | – | – | β-β (16–26 Hz) | 0.002 |
| θ-β (5–27 Hz) | 0.002 | |||||
Connections expressing significant coupling are shown for the control group (Control), PD patients OFF medication (PD-OFF) and PD patients ON medication (PD-ON). P-values are familiywise error (FWE) corrected at the cluster level.