Table 2.
Adverse Events by Arm
| A (N=58) | B (N=29) | p-value | |
|---|---|---|---|
| Overall in all patients | |||
| Grade 3+ | 54 (93.1%) | 26 (89.7%) | 0.681 |
| Grade 4+ | 38 (65.5%) | 16 (55.2%) | 0.342 |
| Grade 3+ Hematologic | 44 (75.9%) | 20 (69.0%) | 0.492 |
| Grade 4+ Hematologic | 32 (55.2%) | 12 (41.4%) | 0.222 |
| Grade 3+ Non-Hematologic | 41 (70.7%) | 13 (44.8%) | 0.012 |
| Grade 4+ Non-Hematologic | 11 (19.0%) | 5 (17.2%) | 0.842 |
| Occurring in at least 10% of patients | |||
| Fatigue Grade 3+ | 8 (13.8%) | 3 (10.3%) | 0.741 |
| Anemia Grade 3+ | 6 (10.3%) | 8 (27.6%) | 0.032 |
| Leukopenia Grade 3+ | 28 (48.3%) | 12 (41.4%) | 0.542 |
| Neutropenia Grade 3+ | 35 (60.3%) | 13 (44.8%) | 0.172 |
| Thrombocytopenia Grade 3+ | 33 (56.9%) | 13 (44.8%) | 0.282 |
1
Fisher Exact
2
Chi-Square