Table 3.
Multiple regression analyses of the range of antibiotic coverage related to various independent clinical determinants
| Dependent variable | Independent determinant | p value |
| Cumulative number of antibiotics | Prior administration of antibiotics | .0001 |
| Presence of a bloodstream infection | .0001 | |
| Positive bronchial cultures | .0001 | |
| Negative outcome | .0001 | |
| Severity of illness (PRISM) | .03 | |
| Development of MOSF | .002 | |
| Immunodeficiency | .001 | |
| Number of central catheters | .03 | |
| Maximum daily number of antibiotics | Interventional TISS | .007 |
| Duration of antibiotic coverage | Length of stay | .0001 |