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. 2014 Oct 10;2:16. doi: 10.1186/2050-5736-2-16

Table 3.

Changes in pain score, analgesic intake, and response

Treatment
 Pain scores (NRS)
 Analgesic intake c
Response d
  Baseline Day 3 1 Month    
1a
 7
 4
 4
 Stable
 PR
1ba
 7
 7
 7
 Stable
 NR
2
 8
 8
 7
 Stable
 NR
3
 8
 9
 2
 Stable
 PR
4
 6
 6
 7
 Stable
 NR
5a
 8
 8
 4
 Reduction
 PR
6
 9
 4
 0
 Increase
 PR
7
 4
 2
 5
 Stable
 NR
5ba
 10
 8
 5
 Reduction
 PR
8
 9
 7
 0
 Stable
 CR
9
 6
 6
 1
 Reduction
 PR
10b
 9
 4
 -
 -
 -
11b 7 7 - - -

Abbreviations: NRS numeric rating scale.

aSecond treatment in the same patient was not included in the response analysis.

bNo follow-up data available at 30 days after treatment, only included in response analysis at 3 days.

cAt 1 month after treatment compared to baseline; reduction is defined as ≥25% decrease in daily oral morphine equivalent (OMED), increase is defined as ≥25% increase in OMED, and stable is defined as neither increase nor decrease [33,34].

dResponse at 1 month as defined by the updated International Bone Metastases Consensus Working Party [33,34]. Partial response (PR): pain reduction of ≥2 or more at the treated site on a 0 to 10 scale without analgesic increase or analgesic reduction without increase in pain. Complete response (CR): pain score of 0 at the treated site with no concomitant increase in analgesics. No response (NR): no partial or complete response.