Table 3.
Hazard Ratio (HR) of Nonaffective Psychoses Among Individuals Born in Sweden 1973–1985 After Hospital Admission With Various Infectious Agents During Childhood
| Type of Infection | Hospital Admission With Infection | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0–13 y | First Year | 1–4 y | 5–9 y | 10–13 y | |||||||||||
| Cases N | Crude HR (95% CI) | Adjusteda HR (95% CI) | Cases N | Crude HR (95% CI) | Adjusteda HR (95% CI) | Cases N | Crude HR (95% CI) | Adjustedb HR (95% CI) | Cases N | Crude HR (95% CI) | Adjustedb HR (95% CI) | Cases N | Crude HR (95% CI) | Adjustedb HR (95% CI) | |
| Any infection | 1114 | 1.27 (1.19–1.36) | 1.10 (1.03–1.18) | 300 | 1.29 (1.15–1.45) | 1.05 (0.93–1.18) | 586 | 1.22 (1.12–1.33) | 1.05 (0.96–1.14) | 290 | 1.31 (1.16–1.47) | 1.17 (1.04–1.32) | 157 | 1.19 (1.01–1.39) | 1.09 (0.93–1.28) |
| Bact infection | 240 | 1.41 (1.24–1.60) | 1.23 (1.08–1.40) | 47 | 1.17 (0.88–1.56) | 0.99 (0.74–1.32) | 92 | 1.51 (1.23–1.86) | 1.30 (1.06–1.60) | 52 | 1.08 (0.82–1.41) | 0.97 (0.74–1.28) | 56 | 1.76 (1.35–2.29) | 1.57 (1.21–2.05) |
| Viral infection | 443 | 1.14 (1.04–1.26) | 0.99 (0.90–1.10) | 108 | 1.18 (0.97–1.42) | 0.98 (0.81–1.19) | 236 | 1.04 (0.91–1.18) | 0.90 (0.79–1.03) | 117 | 1.33 (1.10–1.59) | 1.15 (0.96–1.39) | 33 | 1.17 (0.83–1.65) | 1.01 (0.72–1.43) |
| Other infection | 633 | 1.31 (1.20–1.42) | 1.12 (1.03–1.22) | 168 | 1.41 (1.21–1.65) | 1.11 (0.95–1.29) | 325 | 1.32 (1.18–1.48) | 1.11 (0.99–1.24) | 140 | 1.41 (1.19–1.67) | 1.28 (1.08–1.51) | 82 | 1.06 (0.86–1.32) | 1.00 (0.80–1.25) |
| CNS infection | 45 | 1.38 (1.03–1.86) | 1.22 (0.91–1.64) | 5 | 1.06 (0.44–2.56) | 0.91 (0.38–2.19) | 14 | 1.27 (0.75–2.14) | 1.08 (0.64–1.83) | 17 | 1.36 (0.84–2.18) | 1.22 (0.76–1.96) | 10 | 2.14 (1.15–3.97) | 1.96 (1.05–3.62) |
| Non-CNS infection | 1089 | 1.27 (1.18–1.36) | 1.10 (1.02–1.18) | 299 | 1.29 (1.15–1.45) | 1.06 (0.94–1.19) | 576 | 1.22 (1.11–1.33) | 1.04 (0.96–1.14) | 278 | 1.31 (1.16–1.48) | 1.17 (1.04–1.32) | 150 | 1.17 (0.99–1.37) | 1.07 (0.91–1.26) |
Note: CI, confidence interval.
aAdjusted for male sex, urban birth, parental migration, parental psychiatric history, and hospital admission with other diagnoses.
bAdjusted for male sex, urban birth, parental migration, parental psychiatric history, hospital admission with other diagnoses, and infection during previous time periods.