Table 5.

Risk of Schizophrenia in Offspring Adjusted for Infection in Family Members in a Cohort of 843 390 Persons Born Between 1981 and 1996 of Whom 3409 Cases Developed Schizophrenia During 9.7 Million Person Years of Follow-up

Hospital Diagnosed Infection	Cases	Incidence Rate Ratios (95% CI)
		Basic modela	Fully adjusted modelb
Child
Infection	1549	1.45 (1.35–1.55)	1.37 (1.28–1.47)
No infection	1860	1.00 (reference)	1.00 (reference)
Fatherc
Infection	1076	1.33 (1.23–1.43)	1.21 (1.13–1.31)
No infection	2273	1.00 (reference)	1.00 (reference)
Mother
Infection	1477	1.34 (1.25–1.43)	1.21 (1.13–1.29)
No infection	1932	1.00 (reference)	1.00 (reference)

Note: ^aAdjusted for calendar year, sex, and its interaction with age.

^bFurther adjustment for parental history of mental illness.

^cUnknown father, N = 60, incidence rate ratio: 2.58 (1.98–3.31).