Figure 7. Macrophage infiltration is attenuated in 5-LO-deficient mice subjected to kidney injury.

Mice were treated as described in Fig. 1 (n = 6 per group). Representative immunohistochemical staining for F4/80 in (A) cortical and (B) medullary areas of WT mice and 5-LO-deficient mice treated with saline or BSA (bars  = 40 µm). Quantitative analyses (C,D) were expressed as means ± SE. Statistically significant in relation to *WT+SAL (p<0.05), #WT+BSA (p<0.05), ⁺5-LO^–/–+SAL (p<0.05).