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. Author manuscript; available in PMC: 2014 Oct 10.
Published in final edited form as: Nat Commun. 2013;4:2623. doi: 10.1038/ncomms3623

Figure 4. Conserved and divergent features of Hy.1B11 TCR interaction with self and microbial peptides.

Figure 4

(a–c) Interaction of TCR CDR loops with MBP and microbial peptides. CDR loops that contact MBP (a), PMM (b) and UL15 (c) peptides are shown. TCR residues forming similar contacts with all three peptides are coloured yellow, whereas TCR residues that make different contacts are highlighted in red. Peptide residues are coloured as follows: blue, sequence identity between microbial peptide and MBP; magenta, absence of sequence identity with MBP; green, TCR contact to PMM/UL15 peptides but not MBP peptide.