Figure 12.

GBM data analysis for CNJGL with q = 2. The sample covariance matrices S¹ and S² were generated from samples with two cancer subtypes, with sizes n₁ = 53 and n₂ = 56. Only the 38 genes contained in the Reactome “G2/M checkpoints” pathway were included in this analysis. Of these genes, 15 have been previously identified as regulators. These 15 genes correspond to the last 15 columns in the matrices (columns 24 through 38). CNJGL was performed with λ₁ = 13 and λ₂ = 410. We display (a): the estimated matrix Θ̂¹; (b): the estimated matrix Θ̂². Four of the regulator genes are identified by CNJGL. These genes are CDC6, MCM6, CCNB1, and CCNB2.