Table 4. Linkage and associations with NSCLO, NSCLP and NSCL/P for rs7156227 near BMP4 jointly considering G and interactions with ETS and VIT in Asian trios after those exposed to SMK and ALCOHOL were dropped.
| Race/Site | cleft type | Trios without exposure to any of the four factors | GxETS | P_3df LRT | |||||
| # trios | MAF (%) | OR (95%CI) | P | Power (%) | OR (95%CI) | P | |||
| Asian | NSCLO | 89 | 18.8 | 0.72 (0.41, 1.28) | 2.63*10−1 | 0.9 | 1.71 (0.80, 3.65) | 1.63*10−1 | 3.90*10−1 |
| NSCLP | 282 | 20.5 | 0.54 (0.40, 0.73) | 5.54*10−5 | 59.5 | 1.51 (0.96, 2.38) | 7.32*10−2 | 4.76*10−4 | |
| NSCL/P | 371 | 20.1 | 0.58 (0.44, 0.75) | 4.39*10−5 | 62.3 | 1.60 (1.09, 2.36) | 1.64*10−2 | 4.56*10−4 | |
| Chinese | NSCLO | 75 | 20.0 | 0.78 (0.43, 1.41) | 4.03*10−1 | 0.4 | 1.43 (0.64, 3.22) | 3.84*10−1 | 3.18*10−1 |
| NSCLP | 245 | 20.8 | 0.52 (0.37, 0.71) | 5.74*10−5 | 57.8 | 1.56 (0.96, 2.52) | 7.04*10−2 | 3.50*10−4 | |
| NSCL/P | 320 | 20.6 | 0.57 (0.43, 0.75) | 7.42*10−5 | 57.1 | 1.56 (1.03, 2.35) | 3.43*10−2 | 7.93*10−4 | |
| Taiwan | NSCL/P | 76 | 23.7 | 0.58 (0.35, 0.97) | 3.88*10−2 | 4.8 | 1.45 (0.73, 2.86) | 2.86*10−1 | 1.98*10−1 |
| ShanDong | NSCL/P | 101 | 20.3 | 0.43 (0.25, 0.73) | 1.94*10−3 | 28.0 | 1.77 (0.80, 3.91) | 1.56*10−1 | 1.14*10−2 |