Table 2. Distribution of MTHFR C677T polymorphism genotype by self-reported race and case status.
MTHFR C677T polymorphism genotypes n (%)* | ||||
Self-reported Race | Case Status | CC | CT | TT |
Caucasian American | Cases | 18(33%) | 31(57%) | 5(10%) |
Non-cases | 53(50%) | 43(41%) | 9(9%) | |
African American | Cases | 67(87%) | 8(10%) | 2(3%) |
Non-cases | 184(84%) | 35(16%) | 0(0%) | |
All races | Cases | 85(65%) | 39(30%) | 7(5%) |
Non-cases | 237(73%) | 78(24%) | 9(3%) |
*Allele frequencies of both cases and non-cases in Hardy-Weinberg equilibrium (HWE) for both races.