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. 2014 Oct 10;9(10):e110064. doi: 10.1371/journal.pone.0110064

Table 3. Association of CXCL17 with clinicopathological characteristics.

Nontumoral CXCL17 Peritumoral CXCL17 Intratumoral CXCL17
Variable Low High P Low High P Low High P
Age (year) ≤51 58 58 0.946 62 54 0.320 60 56 0.549
>51 56 55 52 59 53 58
Gender Male 99 98 0.979 100 97 0.676 98 99 0.979
Female 15 15 14 16 15 15
HBsAg Negtive 8 10 0.610 9 9 0.984 9 9 0.984
Positive 106 103 105 104 104 105
Cirrhosis Absent 47 38 0.237 50 35 0.045 49 36 0.067
Present 67 75 64 78 64 78
ALT (U/liter) ≤42 67 71 0.531 68 70 0.723 70 68 0.723
>42 47 42 46 43 43 46
AST (U/liter) ≤42 62 69 0.309 60 71 0.120 64 67 0.745
>42 52 44 54 42 49 47
AFP (ng/ml) ≤25 38 40 0.743 35 43 0.244 33 45 0.103
>25 76 73 79 70 80 69
Tumor size (cm) ≤5 51 45 0.454 48 48 0.955 49 47 0.745
>5 63 68 66 65 64 67
Tumor differentiation I + II 58 71 0.069 54 75 0.004 63 66 0.745
III + IV 56 42 60 38 50 48
Vascular invasion Absent 93 93 0.888 95 91 0.583 95 91 0.406
Present 21 20 19 22 18 23
Tumor multiplicity Solitary 83 87 0.467 83 87 0.467 84 86 0.848
Multiple 31 26 31 26 29 28
Capsulation Absent 23 29 0.325 21 31 0.106 23 29 0.362
Present 91 84 93 82 90 85
TNM stage I + II 67 55 0.127 68 54 0.073 66 56 0.161
III + IV 47 58 46 59 47 58
BCLC stage 0–A 68 68 0.935 69 67 0.850 69 67 0.725
B–C 46 45 45 46 44 47

Note: Underlined terms indicate statistical significance. Abbreviations: AFP: alpha-fetoprotein; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BCLC: Barcelona Clinic Liver Cancer; CI: confidence interval; HBsAg: hepatitis B surface antigen; TNM: tumor-nodes-metastasis.