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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: JAMA Psychiatry. 2014 Jan;71(1):61–70. doi: 10.1001/jamapsychiatry.2013.2833

Figure 1.

Figure 1

(A) Reduced error>correct rACC mean % BOLD signal change in impaired insight cocaine participants (N=15) compared with the other two study groups (unimpaired insight cocaine participants: N=18; healthy controls: N=20) during the color-word Stroop task (with corresponding image, which for display purposes only was thresholded at 2.4≤T≤7.0 and masked by an anatomical ACC region of interest). This reduced error-related rACC activity correlated with (B) more frequent drug use in the last 30 days in all cocaine participants. In parallel, and compared with the other study groups, impaired insight cocaine participants showed lower (C) gray matter volume in the same rACC region; and (D) emotional awareness (LEAS scores). Bar plots show means ± standard errors. Note that BOLD signal values below zero do not necessarily reflect deactivations (as the contrast with error is not with a fixation baseline, but rather with an implicit, active baseline of correct trials; see Methods).