Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 30;13:134. doi: 10.1186/s12933-014-0134-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Qadri et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Methylglyoxal-induced upregulation of NHE1 expression. (A) Representative original Western blot and means ± SEM (n = 4) showing total NHE1 and phospho-NHE1 (14-3-3 binding motif at p-Ser⁷⁰³) determined in MG-treated (0–200 μM for 4 h) EE2 ECs (relative to β-actin). * indicates significant difference (p < 0.05) from 0 μM MG. (B) Mean ± SEM of NHE1 mRNA levels (n = 4) determined in MG-treated (100 μM for 0–8 h) EE2 ECs (relative to β-actin). * indicates significant difference (p < 0.05) from 0 h. (C) Representative original Western blot and means ± SEM (n = 4) showing total NHE1 and phospho-NHE1 (14-3-3 binding motif at p-Ser⁷⁰³; relative to β-actin) determined in excised cremaster muscle 4 h after an intrascrotal injection with saline (Control) or MG (50 mg/kg). * indicates significant difference (p < 0.05) from the absence of MG (Control).