Table 1.
The 20 most abundant microRNAs in blood samples of healthy individuals from 5 studies involving 61 samples
| GSE25609 (n = 20) | GSE53179 (n = 5) | GSE39833 (n = 10) | GSE41922 (n = 22) | GSE50867 (n = 4) | |||||
|---|---|---|---|---|---|---|---|---|---|
| MicroRNA | −Folda | MicroRNA | −Folda | MicroRNA | −Folda | MicroRNA | −Folda | MicroRNA | −Folda |
| hsa-miR-544 | 5.1982 | hsa-miR-451a | 59.1044 | hsa-miR-923 | 199.4318 | hsa-miR-302a | 2.5641 | hsa-miR-451 | 1.4702 |
| hsa-miR-451 | 2.2491 | hsa-miR-486-5p | 28.8059 | hsa-miR-451 | 36.3352 | hsa-miR-145 | 2.3146 | hsa-miR-16 | 1.2892 |
| hsa-miR-302d | 2.1451 | hsa-miR-223-3p | 11.1201 | hsa-miR-1202 | 12.5284 | hsa-miR-551a | 1.5667 | hsa-miR-486-5p | 1.2353 |
| hsa-miR-504 | 2.0654 | hsa-miR-15b-5p | 8.8803 | hsa-miR-1225-5p | 5.1591 | hsa-miR-582-5p | 1.5053 | hsa-miR-19b | 1.1863 |
| hsa-miR-486-5p | 2.0222 | hsa-miR-92a-3p | 8.4054 | hsa-miR-671-5p | 4.0057 | hsa-miR-181c | 1.3988 | hsa-miR-92a | 1.1433 |
| hsa-miR-21 | 2.0120 | hsa-miR-16-5p | 7.0969 | hsa-miR-1299 | 3.4517 | hsa-miR-548c-5p | 1.2898 | hsa-miR-223 | 1.1348 |
| hsa-miR-550 | 1.9378 | hsa-miR-25-3p | 5.7728 | hsa-miR-652 | 1.7898 | hsa-miR-338-3p | 1.2334 | hsa-miR-638 | 1.1233 |
| hsa-let-7a | 1.6534 | hsa-let-7a-5p | 3.1115 | hsa-miR-324-3p | 1.6818 | hsa-miR-142-5p | 1.2326 | hsa-miR-22 | 1.1192 |
| hsa-miR-221 | 1.6534 | hsa-miR-140-3p | 2.3809 | hsa-miR-144 | 1.6222 | hsa-miR-122 | 1.1846 | hsa-miR-1225-5p | 1.1149 |
| hsa-miR-622 | 1.4578 | hsa-miR-107 | 2.0332 | hsa-miR-1268 | 1.4205 | hsa-miR-26b | 1.1733 | hsa-miR-720 | 1.0955 |
| hsa-miR-223 | 1.4578 | hsa-miR-185-5p | 2.0187 | hsa-miR-320d | 1.2528 | hsa-miR-29a | 1.1693 | hsa-miR-21 | 1.0819 |
| hsa-miR-380 | 1.3665 | hsa-miR-30c-5p | 1.9062 | hsa-miR-16 | 1.2386 | hsa-miR-1537 | 1.1631 | hsa-miR-1207-5p | 1.0656 |
| hsa-miR-202 | 1.2831 | hsa-miR-425-5p | 1.7028 | hsa-miR-142-3p | 1.2187 | hsa-miR-199a-5p | 1.1227 | hsa-miR-1915 | 1.0552 |
| hsa-miR-20a | 1.1868 | hsa-miR-22-3p | 1.5608 | hsa-miR-1287 | 1.2159 | hsa-miR-769-5p | 1.1190 | hsa-miR-320c | 1.0464 |
| hsa-miR-122 | 1.1716 | hsa-let-7f-5p | 1.4027 | hsa-miR-1246 | 1.1903 | hsa-let-7i | 1.1175 | hsa-miR-1202 | 1.0456 |
| hsa-let-7g | 1.1232 | hsa-miR-103a-3p | 1.3318 | hsa-miR-223 | 1.1449 | hsa-miR-223 | 1.1106 | hsa-miR-20a | 1.0220 |
| hsa-miR-150 | 1.1087 | hsa-miR-19b-3p | 1.3038 | hsa-miR-188-5p | 1.1420 | hsa-miR-409-3p | 1.1087 | hsa-miR-25 | 1.0161 |
| hsa-miR-551a | 1.0221 | hsa-let-7b-5p | 1.1344 | hsa-miR-513a-5p | 1.1222 | hsa-miR-21 | 1.0196 | hsa-miR-15a | 1.0159 |
| hsa-miR-25 | 1.0052 | hsa-miR-15a-5p | 1.0429 | hsa-miR-760 | 1.0710 | hsa-miR-130b | 1.0092 | hsa-miR-106b | 1.0138 |
| hsa-miR-623 | 1.0000 | hsa-miR-320d | 1.0000 | hsa-miR-720 | 1.0000 | hsa-miR-20aa | 1.0000 | hsa-miR-19a | 1.0000 |
Expression results were downloaded from the Gene Expression Omnibus (GSE25609, GSE53179, GSE39833, GSE41922 and GSE50867). MicroRNAs are ranked by their expression values. The table shows the top 20 microRNA from each study. Data processing and analysis were performed by own programs developed in JAVA program language. MicroRNAs in bold have been found to be relatively abundant in three independent studies. (MicroRNAs denoted with -3p and -5p are transcribed from the same microRNA gene, and represent the two arms of the microRNA precursor)
aValues are calculated in relation the 20th highly expressed microRNA (−fold)