Table 4.
Attributes used in the decision tree
| Attribute ID | Attribute Description |
| I | High-throughput screens (HTS) of interaction |
| I_APMS.TAP | Tandem-affinity purification (TAP) |
| I_APMS.TAP.spoke | Tandem-affinity purification (TAP), "spoke" model |
| I_APMS.HMS-PCI | High-throughput mass spectrometric protein complex identification (HMS-PCI) |
| I_APMS.HMS-PCI.spoke | High-throughput mass spectrometric protein complex identification (HMS-PCI), "spoke" model |
| I_Y2H | Yeast two-hybrid (Y2H) |
| I_Y2H.Uetz | Yeast two-hybrid (Y2H), Uetz et al. |
| X | Correlated mRNA expression |
| X_Rst | Correlated mRNA expression, Rosetta compendium |
| X_Rst.p | Positively correlated mRNA expression, Rosetta compendium |
| X_Rst.p.8 | Correlated mRNA expression, Rosetta compendium, cc > 0.8 |
| X_cc.p | Positively correlated mRNA expression, cell cycle dataset |
| X_cc.p.7 | Correlated mRNA expression, cell cycle dataset, cc > 0.7 |
| X_cc.p.8 | Correlated mRNA expression, cell cycle dataset, cc > 0.8 |
| X_cc.p.9 | Correlated mRNA expression, cell cycle dataset, cc > 0.9 |
| R | Same transcriptional regulator |
| R_p005.ABF1 | Bound by Abf1p, p < 0.005 |
| R_p005.GRF10 | Bound by Grf10p, p < 0.005 |
| R_p005.HAP4 | Bound by Hap4p, p < 0.005 |
| R_p005.RAP1 | Bound by Rap1p, p < 0.005 |
| R_p005.RME1 | Bound by Rme1p, p < 0.005 |
| R_p005.SFP1 | Bound by Sfp1p, p < 0.005 |
| R_p005.SWI4 | Bound by Swi4p, p < 0.005 |
| R_p005.YAP5 | Bound by Yap5p, p < 0.005 |
| R_p001.FHL1 | Bound by Fhl1p, p < 0.001 |
| R_p001.HAP4 | Bound by Hap4p, p < 0.001 |
| R_p001.HIR2 | Bound by Hir2p, p < 0.001 |
| R_p001.RAP1 | Bound by Rap1p, p < 0.001 |
| R_p001.REB1 | Bound by Reb1p, p < 0.001 |
| L | Same subcellular localization (high-throughput) |
| L_05 | ER |
| L_08 | Mitochondrial |
| L_10 | Nucleus |
| L_04 | Cytoplasm |
| P | Same Phenotype |
| P_1 | Conditional phenotypes |
| P_1.1 | Heat-sensitivity |
| P_1.3 | Slow-growth |
| P_2 | Cell cycle defects |
| P_2.4 | Other cell cycle defects |
| P_4.2 | Methionine auxotrophy |
| P_4.5.4 | Respiratory deficiency |
| P_5 | Cell morphology and organelle mutants |
| P_5.2.5 | Other budding mutants |
| P_5.3 | Cell wall mutants |
| P_5.6.1 | Tubulin cytoskeleton mutants |
| P_5.6.1.5 | Other tubulin cytoskeleton mutants |
| P_5.6.2 | Actin cytoskeleton mutants |
| P_5.9 | Secretory mutants |
| P_5.11 | Mitochondrial mutants |
| P_5.13.2 | Other vacuolar mutants |
| P_5.14 | Other cell morphology mutants |
| P_8 | Nucleic acid metabolism defects |
| P_8.1 | DNA repair mutants |
| P_8.1.1 | UV light sensitivity |
| P_8.2 | DNA replication mutants |
| P_9.9 | Staurosporine sensitivity |
| H | Sequence homology, E < e-6 |
| H.e-12 | Sequence homology, E < e-12 |
| N | Gene neighborhood |
| O | Gene co-occurrence |