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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Cancer Immunol Res. 2014 Mar 31;2(7):655–667. doi: 10.1158/2326-6066.CIR-13-0209

Figure 4. Tumor-infiltrating myeloid cells express immunomodulatory genes.

Figure 4

A, Comparison of gene expression profiles of CD11c+ and CD11c− TAMs to Gr1low MDSCs from 4T1 tumor-bearing mice based on 2-fold change (fold-change vs fold-change plot). B, Comparison of gene expression profiles of TANs and Gr1hi MDSCs from 4T1 tumor-bearing mice (fold-change vs t-test P value plot). C, Heatmap generated by hierarchical clustering using probes identified in A and B for all tumor myeloid subsets. D, Heatmap showing the expression of hypoxia-related genes by tumor-associated and steady-state myeloid cells. Selected genes associated with the populations are indicated on the plots.