Figure 1. Vti1a is localized in a peri-nuclear compartment together with syntaxin-6.
- Structured illumination microscopy (3D-SIM) image showing a single optical section through the equatorial plane of a chromaffin cell (top: WT, bottom: vti1a null) stained for vti1a (green) and synaptobrevin-2/VAMP2 (magenta).
- A single optical section of a chromaffin cell (top: WT, bottom: vti1a null) stained for vti1a (green) and syntaxin-6 (magenta), a marker for TGN/immature vesicles/endosomes.
- A single optical section through a chromaffin cell (top: WT, bottom: vti1a null) stained for vti1a (green) and GM130 (magenta), a marker for cis-Golgi.
- A single optical section through a WT chromaffin cell stained for vti1a (green) and TGN38 (magenta), a marker for TGN.
- A single optical section through a WT chromaffin cell stained for syntaxin-6 (green) and TGN38 (magenta).
Data information: Scale bars, 2 μm.