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. 2014 Jul 1;33(15):1713–1726. doi: 10.15252/embj.201387695

Figure 5. Activation of cellular signalling with temporal precision.

Figure 5

  1. Phosphorylation of Opto-mFGFR1 and ERK1/2 in human malignant pleural mesothelioma cells (M38KOpto-mFGFR1, SPC212Opto-mFGFR1) in response to 1 min of blue light followed by indicated duration of darkness.
  2. Phosphorylation of AKT and PLCγ1 in SPC212Opto-mFGFR1 in response to 1 min of blue light followed by indicated lengths of darkness.
  3. mFGFR1-VfAU1-LOV and ERK1/2 phosphorylation in hBEOpto-mFGFR1 cells in response to different durations of blue light.