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. 2014 Mar 11;33(8):783–785. doi: 10.1002/embj.201488223

Figure 1. Tentative model of how Rad17 may help to promote initial MRN recruitment and early damages response signaling at DNA double-strand break sites.

Figure 1

See text for details. Please note that it remains to be determined whether Rad17 acts together with Rfc2-5 as part of an RFC complex in this instance.