Table 1. RBC Unit Parameters and Impact of Washing.
| Wash Device |
Condition | RBC Recovery (%) |
HCT (%) |
Unit Volume (mL) |
Cell Free Volume (mL) |
Wash Time (seconds) |
Glucose (mg/dL) |
Lactate (mg/dL) |
Potassium (mmol/L) |
ATP (μmol/g Hb) |
Hb Sat (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cell Saver Elite (n=20) | Pre-Wash | -- | 65.3±0.9 | 300±6 | 104±3 | -- | 555±26 | 24±1 | 51±1 | 2.74±0.19 | 89±2 |
| Post-Wash | 85±1 | 37.2±0.9* | 449±3* | 282±5* | 730±47 | 66±5* | 5±1* | 1±1* | 2.63±0.18 | 98±1* | |
| Cobe 2991 (n=20) | Pre-Wash | -- | 61.4±1.0† | 288±4 | 111±3 | -- | 579±26 | 24±2 | 50±1 | 2.65±0.11 | 92±2 |
| Post-Wash | 88±2 | 65.8±1.1† | 237±7*† | 82±4*† | 801±45 | 40±3*† | 10±1*† | 2±1*† | 2.57±0.11 | 92±2† |
*
P < 0.05, Pre-Wash vs Post-Wash within a device.
†
P < 0.05, Comparison between two devices (eg Pre Elite vs Pre Cobe, or Post Elite vs Post Cobe). Glucose, Lactate, and Potassium results are expressed in concentration units, and thus do not reflect total unit exposure since they are not corrected for cell free volume as was done for the primary endpoint (cell-free hemoglobin, Figure 2a).