Table 1.
TMA Core | Panel Consensus4 | Number of participant calls on slides stained in their own laboratory
|
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---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | A1 | A2 | A3 | B1 | B2 | B3 | C1 | C2 | C3 | 99 | ||
1 | A1 | 2 | 2 | 2 | 1 | 7 | 19 | 11 | 9 | 15 | 11 | 2 |
2 | A1 | 3 | 7 | 3 | 0 | 3 | 19 | 13 | 9 | 13 | 9 | 2 |
3 | A1 | 1 | 3 | 0 | 1 | 5 | 22 | 8 | 4 | 13 | 22 | 2 |
4 | A1 | 2 | 1 | 1 | 0 | 4 | 7 | 0 | 11 | 22 | 7 | 26 |
5 | 0 | 71 | 2 | 1 | 0 | 2 | 0 | 0 | 2 | 1 | 0 | 2 |
6 | 0 | 72 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 6 |
7 (neg. control) | 0 | 75 | 2 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 1 |
8 (neg. control) | 0 | 49 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 29 |
9 (neg. control) | 0 | 78 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
10 (neg. control) | 0 | 75 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 |
11 | A1 | 2 | 2 | 0 | 1 | 5 | 10 | 8 | 2 | 17 | 33 | 1 |
12 | B1 | 4 | 4 | 3 | 2 | 6 | 11 | 15 | 9 | 9 | 15 | 3 |
13 | C1 | 8 | 11 | 2 | 0 | 22 | 9 | 6 | 12 | 9 | 0 | 2 |
14 | 0 | 28 | 13 | 0 | 0 | 9 | 0 | 0 | 6 | 0 | 0 | 25 |
15 | A1 | 9 | 4 | 0 | 0 | 24 | 4 | 1 | 30 | 7 | 1 | 1 |
16 | A1 | 7 | 9 | 2 | 0 | 18 | 4 | 1 | 21 | 10 | 8 | 1 |
17 | 0 | 39 | 22 | 1 | 0 | 7 | 3 | 0 | 2 | 0 | 2 | 5 |
18 | A1 | 25 | 20 | 0 | 0 | 23 | 2 | 0 | 5 | 0 | 1 | 5 |
19 | A1 | 13 | 17 | 5 | 6 | 2 | 7 | 18 | 0 | 1 | 8 | 4 |
20 | 0 | 16 | 12 | 12 | 4 | 5 | 3 | 18 | 0 | 1 | 6 | 4 |
21 | A1 | 1 | 6 | 3 | 0 | 26 | 6 | 1 | 25 | 9 | 3 | 1 |
22 | C1 | 1 | 0 | 0 | 0 | 2 | 2 | 1 | 25 | 32 | 14 | 4 |
23 | A1 | 4 | 3 | 1 | 0 | 16 | 11 | 1 | 21 | 13 | 7 | 4 |
24 | A1 | 4 | 4 | 0 | 0 | 14 | 8 | 3 | 20 | 9 | 5 | 14 |
25 (pos. cell line) | B3 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 48 | 26 |
Legend (% participants):
Intensity scoring scale: 0 (no staining), A (weak), B (moderate), C (strong).
Percentage (of positive tubular epithelial cell nuclei) scoring scale: 0 (none), 1 (<10%), 2 (10–25%), 3 (>25%).
99 = tissue core cannot be evaluated for technical reasons.
Panel consensus scores for the “reference slide” (i.e. the slide judged by the panel as having the best overall staining intensity, specificity, and lack of background deposition).