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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Thromb Haemost. 2014 Aug 23;12(10):1667–1677. doi: 10.1111/jth.12680

Figure 1.

Figure 1

Quantitative RT-PCR analysis of human CRP transgene expression in mouse livers, inferior vena cavae (IVC), and vein grafts (VGs). (A) Human CRP is expressed in liver, but not IVCs of CRP-Tg donor mice. CRP transgene expression level in liver was sufficient to produce high baseline high levels of human CRP in CRP-Tg mouse plasma (see Fig. 3) and was used as the positive control (assigned expression level 1.0). *P<0.001 vs. all other groups. (B) At 7 days after surgery human CRP transgene expression in livers is significantly increased above donor liver control, but is negligible in VGs. *P<0.001 vs. all other groups. (C) At 28 days after surgery expression of human CRP transgene in livers returns to a level that does not differ significantly from donor liver control (P>0.1) and remains negligible in VGs (*P<0.005 vs. donor liver control).