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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Thromb Haemost. 2014 Aug 23;12(10):1667–1677. doi: 10.1111/jth.12680

Figure 7.

Figure 7

Human CRP enhances fibrin formation in VGs. (A) At 7 days after surgery human CRP significantly increases fibrin formation in mechanically injured VGs (*P<0.001 vs. WTdonor/WTrecipient mice; n=6 mice/group). Below the graph are shown raw fibrin immunostaining data for VGs obtained from 6 mice, 3 in each experimental group, as shown. (B) Spontaneous fibrin deposition is greater in CRP-Tg VGs than in WT VGs. VGs were harvested from WTdonor/WTrecipient mice and CRP-Tgdonor/CRP-Tgrecipient mice (n=6/group) at 28 days after surgery and subjected to fibrin-specific immunostaining. *P<0.02 vs. WT group. Representative images are shown. Red color represents fibrin. Nuclear (DAPI) staining is blue. Scale bar = 200 μm.