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. 2014 Aug 28;234(3):375–385. doi: 10.1002/path.4403

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© 2014 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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NIK is expressed in endothelial cells in tumour tissues. NIK expression in (A) renal carcinoma tissue, (B) breast cancer tissue, (C) pancreatic cancer tissue, (D) melanoma tissue, (E) colorectal cancer tissue, and (F) IF staining on NIK (red), CD31/CD34 (green), and nuclei (blue) in breast cancer tissue. (G) IF staining on NIK (red), phospho-IKKα (green), and nuclei (blue) in breast cancer tissue. (H) IF on NIK (red), CD31/CD34 (green), and nuclei (blue) in normal skin. Representative pictures are shown (n = 5–6 patients or healthy donors, two independent experiments). Scale bars: (A–F, H) 100 µm; (G) 11.2 µm.